Bill Maher appeared in "Return of the King" (voiced by Barry Sobel). During a what-if scenario in which Martin Luther King Jr. survived his assassination attempt, King makes an appearance on Maher's show. When asked about his reaction to the 9/11 attacks, King makes a controversial statement about "turning the other cheek" with America's enemies.
Maher also appeared in "It's a Black President, Huey Freeman" (where he voiced himself this time). When Thugnificent is supporting Barack Obama's presidential campaign, he appears on Bill Maher's show to seem more intelligent. However Maher humiliates Thugnificent by revealing the latter's ignorance of politics.